Dietary treatment of epilepsy: practical implementation of by Elizabeth Neal

By Elizabeth Neal

Epilepsy is a standard continual neurological sickness characterized by means of recurrent unprovoked seizures, and impacts 50 million humans all over the world. nearly 30% of those should not have seizure keep an eye on inspite of the easiest to be had medicines, for that reason renewed and extending curiosity within the use of nutritional remedies to regard epilepsy. those remedies comprise the conventional ketogenic diets but additionally the more moderen converted Atkins vitamin and occasional glycaemic index treatment.
The ketogenic nutrition is a high-fat, adequate-protein, low-carbohydrate nutrition that during medication is used basically to regard refractory epilepsy in young children, and calls for the committed aid of a multi-disciplinary workforce together with medical professionals and dietitians. Dietary therapy of Epilepsy: useful Implementation of Ketogenic Therapy offers accomplished and functional education on all facets of imposing and dealing with nutritional remedies for epilepsy, with key chapters on overview, calculations, implementation, tracking and complications.
Edited via a hugely revered specialist within the box supported via a powerful workforce of members, it is a must-have source for paediatric dietitians and different participants of the treatment crew.

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A. (2007) The neuropharmacology of the ketogenic diet. Pediatr Neurol 36, 281–292. Harvey, J. (2007) Leptin: a diverse regulator of neuronal function. J Neurochem 100, 307–313. J. M. (1971) Medium-chain triglycerides as a therapy for intractable childhood epilepsy. Neurology 21, 1097–1103. , Omote, H. et al. (2010) Metabolic control of vesicular glutamate transport and release. Neuron 68, 99–112. Kawamura, M. N. A. (2010) Metabolic autocrine regulation of neurons involves cooperation among pannexin hemichannels, adenosine receptors, and KATP channels.

2006) Mitochondrial biogenesis in the anticonvulsant mechanism of the ketogenic diet. Ann Neurol 60, 223–235. Cullingford, T. (2008) Peroxisome proliferator-activated receptor alpha and the ketogenic diet. Epilepsia 49 (Suppl. 8), 70–72. , Ungerstedt, U. and Amark, P. (2005) The ketogenic diet influences the levels of excitatory and inhibitory amino acids in the CSF in children with refractory epilepsy. Epilepsy Res 64, 115–125. , Qazi, R. et al. (2006) 2-Deoxy-d-glucose reduces epilepsy progression by NRSF-CtBP-dependent metabolic regulation of chromatin structure.

Most epileptologists do not believe the diet is as effective for partial (focal) onset epilepsy. , 1998); however, others have found it less effective. , 2005). Our experience suggests that the KD is very helpful in managing partial onset epilepsy, and occasionally delays the time until resective surgery is performed, but rarely represents a cure. , 2007). , 2005). , 2005). Five children had seizure-free periods of at least 5 months’ duration. For this syndrome, typically associated with focal epilepsy (due to cortical tubers), the efficacy was surprisingly high.

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