Clinical Trials in Rheumatology by Rüdiger Müller, Johannes von Kempis

By Rüdiger Müller, Johannes von Kempis

With greater than four hundred extant reviews during this box, a determine extra to weekly, it may be demanding to maintain music of rising tendencies. masking the entire stories thus far released, this simple reference is for scientists and clinicians who take care of immunosuppressive medicines.

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5 (HCQ 1200) Adverse events Body as a whole n = 12 (HCQ 400), n = 14 (HCQ 800), n = 7 (HCQ 1200) Central nervous system n = 6 (HCQ 400), n = 12 (HCQ 800), n = 4 (HCQ 1200) Headache n = 1 (HCQ 400), n = 8 (HCQ 800), n = 3 (HCQ 1200) Gastrointestinal n = 19 (HCQ 400), n = 12 (HCQ 800), n = 13 (HCQ 1200) Nausea, vomiting n = 9 (HCQ 400), n = 8 (HCQ 800), n = 7 (HCQ 1200) Hearing n = 2 (HCQ 400), n = 0 (HCQ 800), n = 3 (HCQ 1200) Psychiatric n = 2 (HCQ 400), n = 3 (HCQ 800), n = 0 (HCQ 1200) Respiratory n = 11 (HCQ 400), n = 10 (HCQ 800), n = 11 (HCQ 1200) Skin n = 6 (HCQ 400), n = 6 (HCQ 800), n = 8 (HCQ 1200) Vision n = 5 (HCQ 400), n = 4 (HCQ 800), n = 1 (HCQ 1200) 22 Rheumatoid Arthritis: Hydroxychloroquine HERA-Trial Consequences of delayed therapy with second-line agents in rheumatoid arthritis: a 3 year follow-up on the Hydroxychloroquine in early rheumatoid arthritis (HERA) study HERA: Hydroxychloroquine in early rheumatoid arthritis Substance Hydroxychloroquine 7 mg/kg per day (max.

0 (Dapsone + HCQ) Adverse events Dyspepsia n = 2 (HCQ), n = 2 (Dapsone), n = 3 (Dapsone + HCQ) Anemia n = 0 (HCQ), n = 2 (Dapsone + HCQ), n = 0 (Dapsone + HCQ) Rash n = 1 (HCQ), n = 1 (Dapsone + HCQ) Ulcer bleeding n = 0 (HCQ), n = 1 (Dapsone), n = 0 (Dapsone + HCQ) Rheumatoid Arthritis: Hydroxychloroquine HERA-Trial A randomized trial of Hydroxychloroquine in early rheumatoid arthritis: the HERA Study HERA: Hydroxychloroquine in early rheumatoid arthritis Substance Hydroxychloroquine 7 mg/kg per day (max.

Early intervention appeared to be crucial to limit the development of joint damage in RA patients Patients Early diagnosis of RA Disease duration < 3 years Authors Drosos AA, Voulgari PV, Papadopoulos IA, Politi EN, Georgiou PE, Zikou AK Publication Clin Exp Rheumatol. 5 mg/kg ciclosporin A/day (n = 94) Concomitant medication: Prednisone £ 10 mg/day NSAIDs were permitted Contraception was required Previous medication: Failed parenteral gold Failed D-penicillamine Failed chloroquine/hydroxychloroquine Failed MTX Result 2,5 mg/kg ciclosporin A/day lead to an improvement of the disease activity in RA patients.

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