Chemical Modulators of Protein Misfolding and by Pierfausto Seneci

By Pierfausto Seneci

This publication is a neurochemistry-based significant other for Protein Misfolding and Neurodegenerative ailments: Molecular Targets, an Elsevier identify by way of an identical writer publishing in December 2014. whereas the 1st booklet makes a speciality of biology and molecular ambitions, this significant other booklet describes how those objectives are regulated through small molecules and disease-modifying compounds. The ebook starts off with a quick advent to how key proteins turn into dysfunctional, and every next bankruptcy describes significant affliction mechanisms in Alzheimer’s and different tauopathies. homes and improvement prestige of those molecular goals and ailment mechanisms are completely defined, as are small molecule effectors of autophagy and dis-aggregating brokers.

• Written to supply finished assurance of neurodegenerative disease-modifying compounds;
• offers discipline-specific chapters that conceal medicinal chemistry and scientific applications;
• offers an summary of greater than 2 hundred chemical periods and lead compounds, performing on chosen molecular objectives which are of relevance to any neurodegenerative disorder;
• insurance of misfolding illnesses, chaperone proteins, ubiquitination and autophagy/oncology makes this ebook compatible for structural neurochemists, chemists, biologists, non-CNS scientists, and scientists drawn to drug discovery.

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Additional resources for Chemical Modulators of Protein Misfolding and Neurodegenerative Disease

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