Ankylosing Spondylitis and the Spondyloarthropathies: A by Michael H. Weisman MD, John D. Reveille, Desiree van der

By Michael H. Weisman MD, John D. Reveille, Desiree van der Heijde

Constructed as a significant other textual content to the third version of the heralded Rheumatology, via Hochberg et al., this state of the art reference provides modern figuring out of the spondylarthropathies. you will find thorough examinations of the leading edge, new remedies that problem older innovations of therapy and administration of the illness. famous specialists within the box additionally current the newest strategies in early prognosis utilizing complex imaging options * state of the art wisdom of the pathogenetic and epidemiologic positive aspects * crucial new advancements in immunology * and the newest realizing of the socio-demographic effect of the disease.Describes cutting edge therapy and administration concepts that assist you offer sufferers with vast aid in discomfort, morbidity, and the extra dire effects of the disorder. enables fast connection with the disease's actual manifestations via finished insurance of its scientific facets. enables you to ensure the efficacy of organic brokers in response to the most recent insights on new cures, together with anti-TNF. Assesses the advantages and barriers of obtainable imaging modalities within the analysis and administration of spondylarthropathies.

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Additional info for Ankylosing Spondylitis and the Spondyloarthropathies: A Companion to Rheumatology 3E

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Van der Heijde D, Bellamy N, Cbalin A, et al. Preliminary core sets for endpoints in ankylosing spondylitis. Assessments in Ankylosing Spondylitis Working Group. J Rheumatol. 1997; 24:2225–2229. 106. Hamersma J, Cardon LR, Bradbury L, et al. Is disease severity in ankylosing spondylitis genetically determined? Arthritis Rheum. 2001;44:1396–1400. 107.

J Rheumatol. 2001;28:1288–1293. 59. Vargas-Alarcon G, Londono JD, Hernandez-Pacheco G, et al. Heat shock protein 70 gene polymorphisms in Mexican patients with spondyloarthropathies. Ann Rheum Dis. 2002;61:48–51. 60. Brown MA, Kennedy LG, Darke C, et al. The effect of HLA-DR genes on susceptibility to and severity of ankylosing spondylitis. Arthritis Rheum. 1998;41:460–465. 61. Said-Nahal R, Miceli-Richard C, Gautreau C, et al. The role of HLA genes in familial spondyloarthropathy: a comprehensive study of 70 multiplex families.

Brocke P, Garbi N, Momburg F, Hammerling GJ. HLA-DM, HLADO and tapasin: functional similarities and differences. Curr Opin Immunol. 2002;14:22–29. 16. Deshaies F, Brunet A, Diallo DA, Denzin LK, Samaan A, Thibodeau J. A point mutation in the groove of HLA-DO allows egress from the endoplasmic reticulum independent of HLADM. Proc Natl Acad Sci USA. 2005;102:6443–6448. 17. Paulsson KM. Evolutionary and functional perspectives of the major histocompatibility complex class I antigen-processing machinery.

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