By A. Macieira-Coelho (auth.), Kunio Oota, Masami Iriki, Takashi Makinodan, Lynn S. Baker (eds.)
The challenge of senescence, as mirrored within the historical past of reli gion and philosophy, has lengthy been one of many maximum matters of humankind. against this, gerontology as a department of technological know-how continues to be relatively younger. prior to now decade, concomitant with speedy growth in our figuring out of the fundamental existence sciences, great shops of data approximately organic getting older were amassed. this data, even though, bobbing up from many medical disciplines and involved in various degrees of biologic association, turns out nearly random and covers every little thing from molecules to human societies. Theories complex to interpret the evidence and to appreciate the mech anisms eager about senescence have remained in person, instead of normal, territories. It has lengthy been felt by way of a few gerontologists that it used to be time for a number of the experts to step again and take a generalist view of gerontology, to re-evaluate and reevaluate the end result in their analyt ical ambitions at varied degrees inside a broader context. a few others might imagine it nonetheless untimely. It appeared, notwithstanding, that most of these who accrued in Tokyo at the party of the XIth overseas Congress of Gerontology have been of the opinion that there has been a lot to be received in trying to find interrelationships one of the evidence and theories originated within the varied degrees of investiga tion in an try and become aware of and savor the organic drama of senescence as an entity.
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0 I M X til '" E M Q. U 8 z ..... 0 ~ 0 ::I: ....... ;;: "" 5 5 0- ""u 0 z ..... 0 I t.......... -~ 15 3 MONTHS Fig. 2. 0 15 3 MONTHS Effect of age on incorporation of 3H-glucosamine and 35S- su lfate into glycosaminoglycan. The cartilage slices were incubated in Ham's F-12 medium containing 5 ~Ci of 3H-glucosamine and 5 ~Ci of 35S-sulfuric acid for 3 hr, and the doubly labeled glycosaminoglycan formed was used for subsequent analyses. Experimental details are described in reference (5). Results indicate mean !
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